Induced Pluripotent Stem Cell (iPSC) Core Facility

The iPSC Core Facility is part of the Tissue Culture Support Center within the WUSM Department of Genetics, and supports investigators in all aspects of the generation, maintenance, and differentiation of induced pluripotent stem cells. iPSCs have the potential to become any cell type within the body and are attractive for personalized treatment or regenerative medicine approaches for known genetic disorders.  As iPSCs are patient-derived, they circumvent the ethical issues associated with the destruction of human embryos to generate human embryonic stem cells.  Visit the iPSC Core Facility webpage for additional information.

Core Services

  • Skin Biopsy Processing: The IPSC Core Facility has developed an efficient protocol for the generation of dermal fibroblast cultures from skin punch biopsies.
  • iPSC Generation and Characterization: The Facility offers multiple reprogramming techniques for the generation of induced pluripotent stem cells and offers characterization service of internal- or external-derived lines.
  • Training: The iPSC Facility will work with investigators to provide training related to iPSC maintenance and differentiation.
  • Cryopreservation Services: Cryopreservation for all dermal fibroblast and iPSCs generated within the facility can be arranged.  Contact the Core for current pricing.

Contact: Complete the iPSC Information Form or email Shondra Miller, GEiC Director at smiller@genetics.wustl.edu (314.362.2906).